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SerenEase — Prime Series for Women 40+

SerenEase — Prime Series for Women 40+

Steadier Days Start With Balance Within*

Mood and stress support for women 40+ who want steadier days.

Serotonin shapes more than mood. It influences sleep, appetite, and the general sense of whether a day feels manageable.

SerenEase provides 200mg of 5-HTP from Griffonia simplicifolia seed extract, a naturally occurring precursor the body uses in serotonin production. Carefully selected and aligned with the emotional wellness priorities of life after 40.*

Choosing to invest in your emotional wellness today is part of a broader, more intentional approach to understanding and supporting your health after 40.

No major allergens. Gluten free, lactose free, corn free.

$19.90 USD
$19.90 USD
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  • 30 day money-back guarantee
  • Free US shipping
  • Carefully selected ingredients

Key Benefits

  • Supports normal serotonin levels and emotional well being*
  • 200mg 5-HTP from Griffonia simplicifolia seed extract*
  • Aligned with the emotional wellness priorities of women 40+
  • Manufactured in the USA in an FDA registered facility following cGMP standards
  • Connects with the broader LEAN approach to supplements, health insights, and living well after 40

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Key Ingredients

5-HTP (200mg): 5-hydroxytryptophan from Griffonia simplicifolia seed extract, which supports normal serotonin levels and emotional well being.

Calcium (450mg, 35% Daily Value): a meaningful dose that contributes to daily mineral intake.

Full ingredient list and amounts are shown in the Supplement Facts panel above.

How to Use

Take 2 capsules once daily, 20 to 30 minutes before a meal with an 8 oz glass of water.

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Provides 200 mg of 5-HTP from Griffonia simplicifolia, a precursor involved in normal serotonin production.*

Steadier Days

Serotonin is involved in normal mood and sleep related processes in the body.

Calm Through the Noise

Supports emotional balance as part of a daily wellness routine.*

Balance Within

Your Daily Routine

Begin your routine

Begin your routine

Take 2 capsules once daily, 20 to 30 minutes before a meal with water, as directed on the label.

Make it automatic

Make it automatic

Take it at the same point in your day to make the routine easier to maintain.

Give it the best conditions

Give it the best conditions

Choose a consistent time that follows the label directions and fits your routine.

Pay attention to the fit

Pay attention to the fit

Notice how easily the product fits into your daily wellness routine.

Support the bigger picture

Support the bigger picture

Use it as one part of a broader wellness approach that includes nutrition, activity, sleep and appropriate healthcare.

Science-Backed Ingredients Science-Backed Ingredients
Manufactured in FDA-Registered Facilities Manufactured in FDA-Registered Facilities
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Science-Backed Ingredients Science-Backed Ingredients
Manufactured in FDA-Registered Facilities Manufactured in FDA-Registered Facilities
Subscribe & Save 15% Every Month Subscribe & Save 15% Every Month
Join the LEAN Life Community Join the LEAN Life Community

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FAQ

How are LEAN formulas developed?

Our formulas use carefully selected ingredients at meaningful doses, manufactured in the USA in an FDA registered facility following cGMP standards. We do not claim our finished formulas have been through clinical trials, because they have not. We choose ingredients with published research behind them, at doses consistent with that research, and disclose exactly what is in every bottle.

How do I know which series is right for me?

Prime is formulated for the priorities of life after 40. Platinum is formulated for after 50. The formula is the same within a product; the series reflects the stage of life the guidance is written for. Choose the one that matches where you are.

How should I take this?

Directions are on the product label and in the How to Use section above, since they differ by product. Follow the label.

Is it safe to take with other supplements or medications?

Talk to your doctor or pharmacist before combining supplements, particularly if you take prescription medication. That is true of any supplement, including ours.

What is in it, exactly?

The full Supplement Facts panel and Other Ingredients list are shown on this page. Some formulas use a proprietary blend, where the total is disclosed but individual amounts are not. Where that applies, the panel says so.

Do you have allergens?

Allergen information is listed on every product page. OmegaPure contains fish. FocusFlex contains soy and fish. Some capsules are gelatin based and are not suitable for vegetarians. Check the product page before ordering.

Where do you ship and how long does it take?

We ship across the United States. Orders are fulfilled within one to two business days and typically arrive within three to seven days.

What if it is not right for me?

We offer a 30 day money back guarantee. If it does not suit you, contact Support@LeanNutraceuticals.com and we will make it right.

Customer Reviews

Overall rating: 4.5 / 5 from 270 reviews.

I turned 44 last year and felt like my patience was paper thin every single afternoon. Started taking SerenEase about three weeks ago, and the mood swings have leveled out considerably. I am not snapping at small things anymore. My husband even noticed the difference without me mentioning it.

Sharon 5/5 Verified

SerenEase — Prime Series for Women 40+

I turned 44 last year and felt like my patience was paper thin every single afternoon. Started taking SerenEase about three weeks ago, and the mood swings have leveled out considerably. I am not snapping at small things anymore. My husband even noticed the difference without me mentioning it.

Sharon 5/5

SerenEase — Prime Series for Women 40+

Perimenopause has been a rough ride with sudden anxiety spikes out of nowhere. This supplement has given me a steady sense of calm without making me feel drowsy or foggy. I can finally get through a full workday without feeling overwhelmed.

Isabella N. 5/5 Verified

SerenEase — Prime Series for Women 40+

Perimenopause has been a rough ride with sudden anxiety spikes out of nowhere. This supplement has given me a steady sense of calm without making me feel drowsy or foggy. I can finally get through a full workday without feeling overwhelmed.

Isabella N. 5/5

SerenEase — Prime Series for Women 40+

My afternoon brain fog and irritability have dropped significantly since starting this last month. It took about two weeks to kick in, but now it's an essential part of my morning routine.

Donna R. 5/5 Verified

SerenEase — Prime Series for Women 40+

After hitting 42, my stress levels were through the roof. SerenEase has helped smooth out the edges of my day. I feel much more like myself again.

Sara 5/5 Verified

SerenEase — Prime Series for Women 40+

After hitting 42, my stress levels were through the roof. SerenEase has helped smooth out the edges of my day. I feel much more like myself again.

Sara 5/5

SerenEase — Prime Series for Women 40+

My afternoon brain fog and irritability have dropped significantly since starting this last month. It took about two weeks to kick in, but now it's an essential part of my morning routine.

Donna R. 5/5

SerenEase — Prime Series for Women 40+

It helps me stay calm during busy work projects, but I wish the bottle contained a two-month supply instead of just 30 days.

Nicole A. 4/5 Verified

SerenEase — Prime Series for Women 40+

Super fast shipping and nice packaging. More importantly, it actually helps keep my mood balanced throughout the afternoon.

Janice 5/5 Verified

SerenEase — Prime Series for Women 40+

I've tried several adaptogen blends over the years for hormonal stress. This formula seems to be the most balanced for my body. No jitters, just steady calm.

Nancy K. 5/5 Verified

SerenEase — Prime Series for Women 40+

I've tried several adaptogen blends over the years for hormonal stress. This formula seems to be the most balanced for my body. No jitters, just steady calm.

Nancy K. 5/5

SerenEase — Prime Series for Women 40+

Did not notice any change in my mood or energy levels after three weeks of daily use. Disappointed considering the price.

Theresa_baker8 2/5 Verified

SerenEase — Prime Series for Women 40+

I was skeptical because most supplements don't live up to the hype. But after a month on SerenEase Prime, I feel less jittery and much more grounded. It really helps manage those random hormonal stress spikes.

Cheryl 5/5 Verified

SerenEase — Prime Series for Women 40+

I was skeptical because most supplements don't live up to the hype. But after a month on SerenEase Prime, I feel less jittery and much more grounded. It really helps manage those random hormonal stress spikes.

Cheryl 5/5

SerenEase — Prime Series for Women 40+

My mood swings were driving my family crazy. Since adding this to my morning routine, I feel much more patient and collected.

Megan 5/5 Verified

SerenEase — Prime Series for Women 40+

SerenEase has helped me navigate perimenopause irritability much better. I feel far more balanced and less prone to sudden stress spikes.

Grace A. 5/5 Verified

SerenEase — Prime Series for Women 40+

SerenEase has helped me navigate perimenopause irritability much better. I feel far more balanced and less prone to sudden stress spikes.

Grace A. 5/5

SerenEase — Prime Series for Women 40+