Smooth vegetable capsules that go down easily. Zero aftertaste or stomach burn. Excellent choice for daytime calm and balance.
SerenEase — Platinum Series for Women 50+
SerenEase — Platinum Series for Women 50+
Steadier Days Start With Balance Within*
Serotonin shapes more than mood. It influences sleep, appetite, and the general sense of whether a day feels manageable.
SerenEase provides 200mg of 5-HTP from Griffonia simplicifolia seed extract, a naturally occurring precursor the body uses in serotonin production. Carefully selected and aligned with the emotional wellness priorities of life after 50.*
Choosing to invest in your emotional wellness today is part of a broader, more intentional approach to understanding and supporting your health after 50.
No major allergens. Gluten free, lactose free, corn free.
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30 day money-back guarantee
Free US shipping
Carefully selected ingredients
Key Benefits
- Supports normal serotonin levels and emotional well being*
- 200mg 5-HTP from Griffonia simplicifolia seed extract*
- Aligned with the emotional wellness priorities of women 50+
- Manufactured in the USA in an FDA registered facility following cGMP standards
- Connects with the broader LEAN approach to supplements, health insights, and living well after 50
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Key Ingredients
5-HTP (200mg): 5-hydroxytryptophan from Griffonia simplicifolia seed extract, which supports normal serotonin levels and emotional well being.
Calcium (450mg, 35% Daily Value): a meaningful dose that contributes to daily mineral intake.
Full ingredient list and amounts are shown in the Supplement Facts panel above.
How to Use
Take 2 capsules once daily, 20 to 30 minutes before a meal with an 8 oz glass of water.

Provides 200 mg of 5-HTP from Griffonia simplicifolia, a precursor involved in normal serotonin production.*
Steadier Days
Serotonin is involved in normal mood and sleep related processes in the body.
Calm Through the Noise
Supports emotional balance as part of a daily wellness routine.*
Balance Within
Your Daily Routine

Begin your routine
Take 2 capsules once daily, 20 to 30 minutes before a meal with water, as directed on the label.

Make it automatic
Take it at the same point in your day to make the routine easier to maintain.

Give it the best conditions
Choose a consistent time that follows the label directions and fits your routine.

Pay attention to the fit
Notice how easily the product fits into your daily wellness routine.

Support the bigger picture
Use it as one part of a broader wellness approach that includes nutrition, activity, sleep and appropriate healthcare.
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FAQ
How are LEAN formulas developed?
Our formulas use carefully selected ingredients at meaningful doses, manufactured in the USA in an FDA registered facility following cGMP standards. We do not claim our finished formulas have been through clinical trials, because they have not. We choose ingredients with published research behind them, at doses consistent with that research, and disclose exactly what is in every bottle.
How do I know which series is right for me?
Prime is formulated for the priorities of life after 40. Platinum is formulated for after 50. The formula is the same within a product; the series reflects the stage of life the guidance is written for. Choose the one that matches where you are.
How should I take this?
Directions are on the product label and in the How to Use section above, since they differ by product. Follow the label.
Is it safe to take with other supplements or medications?
Talk to your doctor or pharmacist before combining supplements, particularly if you take prescription medication. That is true of any supplement, including ours.
What is in it, exactly?
The full Supplement Facts panel and Other Ingredients list are shown on this page. Some formulas use a proprietary blend, where the total is disclosed but individual amounts are not. Where that applies, the panel says so.
Do you have allergens?
Allergen information is listed on every product page. OmegaPure contains fish. FocusFlex contains soy and fish. Some capsules are gelatin based and are not suitable for vegetarians. Check the product page before ordering.
Where do you ship and how long does it take?
We ship across the United States. Orders are fulfilled within one to two business days and typically arrive within three to seven days.
What if it is not right for me?
We offer a 30 day money back guarantee. If it does not suit you, contact Support@LeanNutraceuticals.com and we will make it right.
Customer Reviews
Overall rating: 4.7 / 5 from 262 reviews.
Smooth vegetable capsules that go down easily. Zero aftertaste or stomach burn. Excellent choice for daytime calm and balance.
Jennifer 5/5
Works as advertised for mild daily stress, though I wish it came in a 90-day bottle option.
Harper 4/5 Verified
Works as advertised for mild daily stress, though I wish it came in a 90-day bottle option.
Harper 4/5
Formulated thoughtfully to address mood changes as women age. Great product from a brand I trust!
Maria R. 5/5 Verified
Formulated thoughtfully to address mood changes as women age. Great product from a brand I trust!
Maria R. 5/5
After turning 53, I noticed my tolerance for stress plummeted and I felt easily overwhelmed. SerenEase has helped restore my emotional balance. Easy to pop with breakfast every morning.
Christine 5/5 Verified
After turning 53, I noticed my tolerance for stress plummeted and I felt easily overwhelmed. SerenEase has helped restore my emotional balance. Easy to pop with breakfast every morning.
Christine 5/5
No stomach upset, which is always a bonus with herbal supplements. Smooth capsule shell makes swallowing easy every morning.
Cheryl 5/5 Verified
No stomach upset, which is always a bonus with herbal supplements. Smooth capsule shell makes swallowing easy every morning.
Cheryl 5/5
My wellness practitioner suggested an adaptogenic stress blend to support hormonal balance and mood in my 50s. After trying a couple of other brands that did nothing, this one actually helped within a week. My daily stress levels feel much more manageable now.
Stephanie_x23 5/5 Verified
Good product overall, but shipping took six days instead of three. The supplement itself works well for mild anxiety and moodiness.
Kelly V. 4/5 Verified
Taking one capsule in the morning with breakfast has become automatic for me. Zero unpleasant aftertaste or stomach upset. Really pleased with the clean, thoughtful formulation.
Kathleen 5/5 Verified
High quality adaptogenic blend tailored specifically for mature women. Cleanly sourced and works as advertised!
Gloria R. 5/5 Verified
High quality adaptogenic blend tailored specifically for mature women. Cleanly sourced and works as advertised!
Gloria R. 5/5
Taking one capsule in the morning with breakfast has become automatic for me. Zero unpleasant aftertaste or stomach upset. Really pleased with the clean, thoughtful formulation.
Kathleen 5/5
Good product overall, but shipping took six days instead of three. The supplement itself works well for mild anxiety and moodiness.
Kelly V. 4/5
My wellness practitioner suggested an adaptogenic stress blend to support hormonal balance and mood in my 50s. After trying a couple of other brands that did nothing, this one actually helped within a week. My daily stress levels feel much more manageable now.
Stephanie_x23 5/5
High potency and clean ingredients. I love knowing I’m supporting my nervous system naturally without synthetic additives.
Brenda 5/5 Verified
High potency and clean ingredients. I love knowing I’m supporting my nervous system naturally without synthetic additives.
Brenda 5/5
I’ve been taking SerenEase for about three weeks now, and I notice a genuine sense of calm throughout my workday. I used to feel overwhelmed by afternoon stress, but now I handle busy days much more smoothly. The capsules are easy to swallow and don't make me drowsy.
Anna 5/5 Verified
I’ve been taking SerenEase for about three weeks now, and I notice a genuine sense of calm throughout my workday. I used to feel overwhelmed by afternoon stress, but now I handle busy days much more smoothly. The capsules are easy to swallow and don't make me drowsy.
Anna 5/5
Good mood product. High quality ingredients and sturdy bottle. Will reorder when running low.
Virginia M. 5/5 Verified
Good mood product. High quality ingredients and sturdy bottle. Will reorder when running low.
Virginia M. 5/5
Noticeable reduction in feeling overwhelmed during hectic afternoons. Highly recommend for any woman in her 50s.
Cheryl B. 5/5 Verified
Noticeable reduction in feeling overwhelmed during hectic afternoons. Highly recommend for any woman in her 50s.
Cheryl B. 5/5
Finally a mood balance supplement tailored specifically for women going through hormonal shifts in their 50s. I feel less tense in my shoulders and my mind feels clear. Zero odor when opening the seal.
Melissa 5/5 Verified
Finally a mood balance supplement tailored specifically for women going through hormonal shifts in their 50s. I feel less tense in my shoulders and my mind feels clear. Zero odor when opening the seal.
Melissa 5/5
Excellent mood formula. I appreciate that it's specifically formulated for women 50+ dealing with natural age-related mood fluctuations. Feels like a high-grade product.
Sara 5/5 Verified
Excellent mood formula. I appreciate that it's specifically formulated for women 50+ dealing with natural age-related mood fluctuations. Feels like a high-grade product.
Sara 5/5
Completely gentle formula! I take one pill every morning after breakfast with zero side effects.
Pamela_girl87 5/5 Verified
Completely gentle formula! I take one pill every morning after breakfast with zero side effects.
Pamela_girl87 5/5
Great stress support! I noticed my nervous energy has calmed down considerably after 3 weeks of taking SerenEase.
Amy 5/5 Verified
Great stress support! I noticed my nervous energy has calmed down considerably after 3 weeks of taking SerenEase.
Amy 5/5
Good product, but the exterior bottle label was printed slightly crooked. Content inside is top quality though.
B_torres7 4/5 Verified
Cleanest calm supplement I’ve used so far. Zero brain fog and no herbal aftertaste after taking it.
Heather 5/5 Verified
Good product, but the exterior bottle label was printed slightly crooked. Content inside is top quality though.
B_torres7 4/5
Cleanest calm supplement I’ve used so far. Zero brain fog and no herbal aftertaste after taking it.
Heather 5/5
Easy to digest. I like that it uses high quality adaptogens specifically chosen for women's health needs after 50.
Beverly 5/5 Verified
Easy to digest. I like that it uses high quality adaptogens specifically chosen for women's health needs after 50.
Beverly 5/5
