No amount of coffee could reduce my fatigue but a few weeks of this supplement did. I feel so much better and no longer feel like I’m going to fall asleep during the middle of the day. It’s so nice to have energy to live my life again.
NAD+ — Prime Series for Men 40+
NAD+ — Prime Series for Men 40+
Invest in Your Cells Today. Feel It for Decades.*
At 40, most men are focused on what they can see and feel: energy, strength, recovery. But the foundation of all of it starts at the cellular level. NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell, playing a key role in energy production, metabolic function, and cellular repair processes.
LEAN NAD+ delivers 500mg of NAD+ alongside Quercetin (250mg) for immune and inflammatory response support, and Japanese Knotweed Resveratrol (150mg, 98% purity) for cardiovascular and cognitive wellness.* Together, these three ingredients support your body's cellular resilience from multiple angles.
Being proactive about your cellular health today is part of a more intentional approach to understanding and supporting your health after 40.
No major allergens listed. Vegetable capsule. Free from gluten, dairy, soy, and lactose.
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30 day money-back guarantee
Free US shipping
Carefully selected ingredients
Key Benefits
- 500mg NAD+ for cellular energy and metabolic support*
- Enhanced with Quercetin and Resveratrol for comprehensive cellular wellness*
- Manufactured in the USA in an FDA registered facility following cGMP standards
- One part of LEAN's connected approach to understanding your health, supporting your wellness, and enjoying more of life
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Key Ingredients
NAD+ (500 mg): Nicotinamide Adenine Dinucleotide, a vital coenzyme present in every cell of your body. NAD+ plays a key role in cellular energy production, metabolic function, and DNA repair processes.*
Quercetin Dihydrate Extract (250 mg): a naturally occurring flavonoid that supports a normal inflammatory response and optimal immune function.*
Japanese Knotweed Resveratrol (150 mg, 98% purity): a potent antioxidant sourced from Polygonum cuspidatum root, studied for its role in supporting cardiovascular health and cognitive wellness.*
Full ingredient list and amounts are shown in the Supplement Facts panel above.
How to Use
Take 2 capsules daily with a meal, or as directed by a healthcare professional.
For best results, take consistently at the same time each day. Store in a cool, dry place.

Provides 500 mg of NAD+, a coenzyme involved in normal cellular energy processes.*
Recharge From Within
Quercetin and resveratrol add complementary antioxidant support to the formula.*
Energy at the Cellular Level
Supports normal cellular energy processes as part of a healthy aging routine.*
Support Energy From Within
Your Daily Routine

Begin your routine
Take 2 capsules daily with a meal, as directed on the product label.

Make it automatic
Take it at the same point in your day to make the routine easier to maintain.

Give it the best conditions
Morning may be a convenient time if it helps you maintain consistent daily use.

Pay attention to the fit
Notice how easily the product fits into your daily wellness routine.

Support the bigger picture
Use it as one part of a broader wellness approach that includes nutrition, activity, sleep and appropriate healthcare.
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FAQ
How are LEAN formulas developed?
Our formulas use carefully selected ingredients at meaningful doses, manufactured in the USA in an FDA registered facility following cGMP standards. We do not claim our finished formulas have been through clinical trials, because they have not. We choose ingredients with published research behind them, at doses consistent with that research, and disclose exactly what is in every bottle.
How do I know which series is right for me?
Prime is formulated for the priorities of life after 40. Platinum is formulated for after 50. The formula is the same within a product; the series reflects the stage of life the guidance is written for. Choose the one that matches where you are.
How should I take this?
Directions are on the product label and in the How to Use section above, since they differ by product. Follow the label.
Is it safe to take with other supplements or medications?
Talk to your doctor or pharmacist before combining supplements, particularly if you take prescription medication. That is true of any supplement, including ours.
What is in it, exactly?
The full Supplement Facts panel and Other Ingredients list are shown on this page. Some formulas use a proprietary blend, where the total is disclosed but individual amounts are not. Where that applies, the panel says so.
Do you have allergens?
Allergen information is listed on every product page. OmegaPure contains fish. FocusFlex contains soy and fish. Some capsules are gelatin based and are not suitable for vegetarians. Check the product page before ordering.
Where do you ship and how long does it take?
We ship across the United States. Orders are fulfilled within one to two business days and typically arrive within three to seven days.
What if it is not right for me?
We offer a 30 day money back guarantee. If it does not suit you, contact Support@LeanNutraceuticals.com and we will make it right.
Customer Reviews
Overall rating: 4.6 / 5 from 666 reviews.
No amount of coffee could reduce my fatigue but a few weeks of this supplement did. I feel so much better and no longer feel like I’m going to fall asleep during the middle of the day. It’s so nice to have energy to live my life again.
Luke 5/5
Excellent anti-aging supplement for active men over 40. Smooth digestion and zero strange aftertaste.
William 5/5 Verified
I take two capsules daily with my morning breakfast. Noticeable reduction in muscle soreness after my gym sessions, and my recovery time feels much faster.
Oliver 5/5 Verified
Excellent anti-aging supplement for active men over 40. Smooth digestion and zero strange aftertaste.
William 5/5
I take two capsules daily with my morning breakfast. Noticeable reduction in muscle soreness after my gym sessions, and my recovery time feels much faster.
Oliver 5/5
I started taking 500mg daily upon receiving the NAD+ and felt Normal. It kept me awake and feeling strong for a long time into the night. I advise not taking before bed as it will keep you up. It a great product that yielded quick results for me.
W_gonzalez1 5/5 Verified
Easy on the digestive tract with a clean ingredient list. My nutritionist recommended boosting NAD+ as I get older, and this product hits the mark.
Roy Q. 5/5 Verified
Easy on the digestive tract with a clean ingredient list. My nutritionist recommended boosting NAD+ as I get older, and this product hits the mark.
Roy Q. 5/5
I started taking 500mg daily upon receiving the NAD+ and felt Normal. It kept me awake and feeling strong for a long time into the night. I advise not taking before bed as it will keep you up. It a great product that yielded quick results for me.
W_gonzalez1 5/5
Taking pills twice a day is simple enough, though I wish the bottle came with 90 capsules instead of 60.
Gerald M. 4/5 Verified
Taking pills twice a day is simple enough, though I wish the bottle came with 90 capsules instead of 60.
Gerald M. 4/5
Five stars without a doubt. As an executive working 60-hour weeks, afternoon brain fog was killing my productivity. NAD+ Prime cleared that right up.
Jeremy R. 5/5 Verified
I love it, I take it every day in the morning and it helped me a lot with the appearance of my skin.
Isaac V. 4/5 Verified
Fast dispatch from LEAN Nutraceuticals. The capsules are smooth and slide down easily with a glass of water.
Gerald 5/5 Verified
Five stars without a doubt. As an executive working 60-hour weeks, afternoon brain fog was killing my productivity. NAD+ Prime cleared that right up.
Jeremy R. 5/5
Fast dispatch from LEAN Nutraceuticals. The capsules are smooth and slide down easily with a glass of water.
Gerald 5/5
I love it, I take it every day in the morning and it helped me a lot with the appearance of my skin.
Isaac V. 4/5
Excellent quality. I've already recommended NAD+ Prime to a few friends in my age bracket who were complaining about mid-day exhaustion.
Brandon_wilson50 5/5 Verified
Perfect addition to my morning supplement routine. The boost in mental sharpess and daily energy is very real.
Mason O. 5/5 Verified
Excellent quality. I've already recommended NAD+ Prime to a few friends in my age bracket who were complaining about mid-day exhaustion.
Brandon_wilson50 5/5
Perfect addition to my morning supplement routine. The boost in mental sharpess and daily energy is very real.
Mason O. 5/5
Solid product, but a bit on the expensive side unless you sign up for the monthly subscription discount.
Nathan 4/5 Verified
I'm 52 and started taking cellular longevity seriously last year. This supplement keeps my energy feeling natural and sustained all day.
Hunter J. 5/5 Verified
Solid product, but a bit on the expensive side unless you sign up for the monthly subscription discount.
Nathan 4/5
I'm 52 and started taking cellular longevity seriously last year. This supplement keeps my energy feeling natural and sustained all day.
Hunter J. 5/5
Didn't notice much difference after 10 days of use. Maybe it takes a few months to accumulate in the system, but I expected quicker results.
Scott 3/5 Verified
Didn't notice much difference after 10 days of use. Maybe it takes a few months to accumulate in the system, but I expected quicker results.
Scott 3/5
It's super good I've only been two weeks and it gives a lot of energy.
Kyle 5/5 Verified
Capsules are slightly large, but manageable if you take them with a full glass of water during breakfast.
Louis 4/5 Verified
Clean presentation with zero stomach upset. That's a major win for me since most vitamins cause acid reflux.
Vincent T. 5/5 Verified
It's super good I've only been two weeks and it gives a lot of energy.
Kyle 5/5
Capsules are slightly large, but manageable if you take them with a full glass of water during breakfast.
Louis 4/5
Clean presentation with zero stomach upset. That's a major win for me since most vitamins cause acid reflux.
Vincent T. 5/5
I have taken this supplement for a couple years for my brain health. I feel better and know it works for me.
Elijah 5/5 Verified
I have taken this supplement for a couple years for my brain health. I feel better and know it works for me.
Elijah 5/5
A bit pricier than basic drug store vitamins, but the higher quality formula and purity make it worth every penny.
Kenneth 4/5 Verified
Was skeptical at first, but after 30 days I can power through a full workday and still have energy to play catch with my kids.
Richard 5/5 Verified
A bit pricier than basic drug store vitamins, but the higher quality formula and purity make it worth every penny.
Kenneth 4/5
Was skeptical at first, but after 30 days I can power through a full workday and still have energy to play catch with my kids.
Richard 5/5
